Lithium-Induced Acute Renal Failure SIGNS AND SYMPTOMS OF TOXIC EFFECTS OF LITHIUM Signs and Symptoms
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FIGURE 11-13 (see Color Plate) Intravascular coagulation in a cyclosporine-treated renal transplant recipient. Cyclosporine produces a dose-related decrease in renal function in experimental animals and humans [17] that is attributed to the drug’s hemodynamic action to produce vasoconstriction of the afferent arteriole entering the glomerulus. When severe enough, this can decrease glomerular filtration rate. Although the precise pathogenesis of the renal hemodynamic effects of cyclosporine are unclear, endothelin, inhibition of nitric oxide, Cyclosporine
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تاریخ انتشار 2000